Define your analog generation parameters.
Select which chemical modifications to apply.
Add/replace simple substituents.
e.g., COOH ↔ tetrazole
H ↔ F/Cl/Br on aryl positions
Modify ring sizes.
e.g., O↔S, NH↔O
Add/remove ±CH₂ units
Cyclize a flexible linker.
Fill out the configuration and click "Generate Analogs".